Peer-reviewed Publications:(**) denotes corresponding author
[10] Oraby, A.K.; Bilawchuk, L; West, F.G.; Marchant, D.J., Structure-Based Discovery of Allosteric Inhibitors Targeting a New Druggable Site in the Respiratory Syncytial Virus Polymerase. ACS Omega, 2024, 9 (20), 22213-22229 (link)
[9] Oraby, A.K., Marchant, D.J. CCHFV entry via LDLR keeps it ‘ticking’?. Cell Res (2024). https://doi.org/10.1038/s41422-024-00928-1

 

[8] Hayes, R.S.; Oraby, A.K.; Camargo, C.; Marchant, D.J.; Sagan, S.M., Mapping respiratory syncytial virus fusion protein interactions with the receptor IGF1R and the impact of alanine-scanning mutagenesis on viral infection. J. Gen. Virol., 2024, 1. (link)

[7] Rana, N.; Aziz, M. A.; Oraby, A. K.; Wuest, M.; Dufour, J.; Abouzid, K. A. M.; Wuest, F.; West, F. G., Towards Selective Binding to the GLUT5 Transporter: Synthesis, Molecular Dynamics and In Vitro Evaluation of Novel C-3-Modified 2,5-Anhydro-D-mannitol Analogs. Pharmaceutics, 2022, 14. (link)

[6] Oraby, A.K.; Gardner, C.L.; Needle, R.F.; Kofahi, H.M.; Everard, K.R.; Taylor, N.G.A.; Rutihinda, S.G.; Barry, J.P.; Hirasawa, K.; Georghiou, P.E.; Russell, R.S., A Novel Small-Molecule Inhibits Hepatitis C Virus Propagation in Cell Culture. Microbiol. Spectr.,2021, 9:e00439-21. (pdf)
[5] Elawar, F.; Oraby, A.K.; Kieser,Q.; Jensen, L.D.; West, F.G.; Marchant, D.J., Pharmacological Targets and Emerging Treatments for Respiratory Syncytial Virus Bronchiolitis. Pharmacol. Therapeut., 2021, 220, 107712. (pdf)
[4] Oraby, A.K.**; Abdellatif, K.A.R; Abdelgawad, M.A; Attia, K.M; Dawe, L.N.; Georghiou, P.E.**,2,4‐Disubstituted Phenylhydrazonopyrazolone and Isoxazolone Derivatives as Antibacterial Agents: Synthesis, Preliminary Biological Evaluation and Docking Studies. ChemistrySelect, 2018, 3, 3295-3301. (pdf)
[3] Oraby, A.K.; Abdellatif, K.A.R; Abdelgawad, M.A; Attia, K.M; Georghiou, P.E., Synthesis and Antimicrobial Activities of a Series of Disubstitutedarylazo-Barbituric- and Thiobarbituric Acid Derivatives. Int. J. Pharm. Chem., 2016, 6, 100-106. (pdf)

[2] Alodhayb, A.N; Braim, M; Valluru, G.; Beaulieu, L.Y; Rahman, S; Oraby, A.K.; Georghiou, P.E., Metal ion binding properties of a bimodal triazolyl-functionalized calix[4]arene on a multi-array microcantilever system. Synthesis, fluorescence and DFT computation studies. RSC Adv., 2016, 6, 4387-4396. (pdf)

 [1] Rahman, S; Assiri, Y; Alodhayb, A.N; Beaulieu, L.Y; Oraby, A.K.; Georghiou, P.E., Naphthyl “capped” triazole-linked calix[4]arene hosts as fluorescent chemosensors towards Fe3+ and Hg2+: an experimental and DFT computational study. New J. Chem., 2016, 40, 434-440. (pdf)
 

Preprints:

[1] Ahmed K. Oraby, Aleksandra Stojic, Farah Elawar et al. A Single Amino Acid Mutation Alters the Neutralization Epitopes in the Respiratory Syncytial Virus Fusion Glycoprotein, 05 March 2024, PREPRINT available at Research Square (Link)